August 25, 2025
Dehydration is common during cancer treatment, and it occurs when you lose more fluid than you take in. Staying hydrated helps your kidneys work properly, protects your overall health, and reduces your chance of needing emergency care.
When you're dehydrated, your body struggles to balance important salts and minerals. This imbalance can make you feel worse and can even affect your treatment schedule.
Let’s quickly look at why dehydration happens during treatment.
Chemotherapy and radiation, along with some medications, often cause side effects that lead to dehydration. These treatments can irritate your stomach and gut lining, triggering fluid loss.
The main reasons for dehydration during cancer treatment include:
Radiation treatments targeting the head and neck can particularly affect saliva glands, making swallowing fluids difficult.
Now that you know the why, here’s how to stay ahead day to day.

Drinking enough fluids daily is your first defense against dehydration. Everyone’s needs are different based on their treatment, age, and side effects, but a good rule is about eight glasses of water daily.
Keep water close and make sipping easy:
Foods high in water content can also boost your hydration. These include:
You should also limit drinks that make dehydration worse, such as alcoholic and caffeinated beverages. Alcohol increases fluid loss, while caffeine can make you urinate more.
When nausea, vomiting, or diarrhea strikes, electrolyte drinks help by replacing fluids and the salts and minerals your body loses. Commercial oral rehydration solutions (ORS) typically come in packets mixed into one liter of clean water.
If commercial ORS isn’t available, a homemade drink can temporarily help. Here’s a simple mix:
Before using homemade solutions, talk to your care team, especially if symptoms are severe. Tracking what goes in and out helps you spot problems early.
Keeping an eye on your fluid intake helps you stay hydrated. Using a measured water bottle or cup can make tracking easier. Check these simple indicators daily:
A few food swaps also make hydration easier.
Small, frequent meals are easier on your stomach, helping you avoid nausea and stay hydrated. Greasy or spicy foods might irritate your stomach and increase fluid loss, so choose gentle foods instead.
If your doctor suggests oral rehydration solutions, you may try brands designed specifically for hydration, especially if symptoms persist.
Know the warning signs that means you should call us now.
Certain symptoms can indicate serious dehydration and require immediate medical attention:
Severe dehydration can impact the effectiveness of cancer treatment and increase the risk of infection by weakening the immune system. In severe cases, dehydration can also lead to organ failure.
It’s crucial to consult a healthcare provider, who can evaluate the symptoms and recommend an appropriate course of treatment, which may include intravenous fluids, electrolyte replacement, or other interventions.
If you have any questions or concerns about the risk of dehydration during cancer treatment, contact ACTC, one of the best cancer treatment centers in Florida.
ACTC offers personalized cancer care plans and treatments. Call 352-345-4565 or book an appointment.

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