A rare and highly aggressive variety of pediatric carcinoma, Malignant Rhabdoid Tumor or MRT is usually not handled very well due to lack of sufficient knowledge about it. Read on to get a better understanding of this disease and to learn about some of the common treatment plans that are implemented to deal with it.
MRT is a condition that is detected in about 25 children in the United States every year. It is common to see this disease in very young children, especially infants and toddlers. Such tumors are mostly found in the kidneys and are known for metastasizing at a very high speed. While no research findings have been able to pinpoint the exact cause of an MRT tumor in the kidneys, years of focused investigation has revealed that in a majority of such tumors, a particular gene known as the SMARCB1 is mutated. This gene is a tumor suppressor gene and, therefore, when it is abnormally mutated, it loses its ability to protect cells from cancerous growths.
Symptoms of MRT:
Diagnosis of MRT:
A set of procedures can help you find out what type of tumor is present in your child’s kidney. These tests are also beneficial in figuring out if cancer has metastasized, and if so, what other areas of the body has it taken over. Aside from a thorough physical examination, here are some diagnostic methods used for MRTs:
Treatment Options For MRT:
A combined medley of treatment protocols is used together to treat MRTs. The appropriate mix of treatment options is decided on a case by case basis. Here is a list of these procedures:
MRT survivors may have to lead their lives with several long-term effects of the cancer therapies that they have undergone, as well as a constant threat of development of secondary cancers. It is, therefore, essential to ensure that they get themselves checked every year to manage all the fallouts of MRT post-treatment.
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